Modeling Experimental Design for Big Mechanisms

Here, we model the data structure based on 'observables' within systems biology studies to develop a library of 'motif's that may be composed together to represent the scientific observations generated within studies of cancer pathways.

View the Project on GitHub BMKEG/bigMechKefedJavaWorkbook

Pages indexed by Month and Year

June 2016

July 2015

May 2015

April 2015

January 2015

December 2014

October 2014

August 2014

This is concerned with our efforts to apply the KEfED methodology ( to the study of cancer pathways as part of the Big Mechanisms DARPA program. Here, we strive to apply this approach to systems biology, making it more agile and effective and supporting multiple activities including text mining and modeling efforts.

This website provides evolving, dynamic technical documentation for research work within the RUBICON group of the DARPA Big Mechanism project.

If you have any questions, feedback or issues concerning this work, contact us at